Place of Origin: | China |
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Brand Name: | HNB |
Certification: | ISO |
Model Number: | 5-Fluorouracil |
Minimum Order Quantity: | 1KG |
Price: | Negotiable |
Packaging Details: | Aluminum foil bag |
Delivery Time: | Usually3-5days |
Payment Terms: | L/C, D/A, D/P, T/T, , MoneyGram,Alibaba Assurance Order |
Supply Ability: | 5000kg/Month |
CAS: | 51-21-8 | Mf: | C4H3FN2O2 |
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MW: | 130.077 | Specification: | 99% |
Flash Point: | 196.5 ℃ | Appearance: | White Powder |
EINECS: | 200-085-6 | Sample: | Available |
Whatsapp: | 86 15202961574 | ||
High Light: | 5-Fluorouracil Powder,Antimetabolite Drug 5-FU,API Pharmaceutical 51-21-8 |
API Pharmaceutical CAS 51-21-8 Antimetabolic Drug 99% 5-FU 5-Fluorouracil
Product name |
5-Fluorouracil |
Appearance |
White Powder |
CAS |
133876-92-3 |
MF |
C4H3FN2O2 |
Purity |
99% |
Storage |
Keep in cool dry place. |
whatsapp:+86 15202961574
The Introductction of 5-Fluorouracil
5-Fluorouracil, also known as 5-fluorouracil, with the chemical formula of C4H3FN2O2, is a pyrimidine analogue and an antimetabolic drug, mainly used to treat tumors.
The Application & Function of 5-Fluorouracil
5-Fluorouracil has certain curative effect on various tumors, such as digestive tract tumors, breast cancer, ovarian cancer, choriocarcinoma, cervical cancer, liver cancer, bladder cancer cancer, skin cancer (local application), vulva leukoplakia (local application), etc. It is used alone or in combination with other drugs for adjuvant treatment of breast cancer and gastrointestinal tumors, as well as for palliative treatment of some non-surgical malignant tumors, especially those of the gastrointestinal tract, breast, head and neck, liver, urinary system and pancreas.
Previous experience shows that the partial response rate of 5-FU to metastatic breast cancer and gastrointestinal sarcoma is 10%~30%. The combination of 5-FU and some other drugs can often achieve high response rate and survival rate. For example, the combination of cyclophosphamide and MTX (breast cancer), cisplatin (ovarian and head and neck cancer), and hydrofolate (colorectal cancer) can increase the 5-UF activity, but also increase its toxicity. 5-FU combined with levamisole (immunostimulation, weak side effects) can reduce the recurrence rate of colorectal cancer and improve the postoperative survival rate. 5-FU local external application is effective in the treatment of skin basal cell carcinoma, as well as severe refractory psoriasis
5-FU, also known as 5-fluorouracil, is a thymidine synthase inhibitor. 5-FU mainly inhibits deoxythymidine synthase by transforming into 5-fluorouracil deoxynucleotide in cells, prevents deoxyuridylate methyl from being converted into deoxythymidylate, and intervenes in DNA synthesis to play a role. It is mainly used for the treatment of digestive system cancer, ovarian cancer, cervical cancer, breast cancer, malignant mole, bladder cancer, skin cancer, head and neck cancer and other diseases, 5-FU oral malabsorption, mainly through intravenous administration. During the administration of 5-FU, it has a great toxic effect on bone marrow and digestive tract, and some people may have alopecia, skin pigmentation, liver and kidney damage and other adverse reactions, which should be observed.
The COA of 5-Fluorouracil
ITEMS OF ANALYSIS |
SPECIFICATION
|
RESULT |
Characteristics | White crystalline powder, odorless or practically odorless and practically tasteless | Complies |
Identification | IR: The infrared absorption spectrum should be concordant with the reference spectrum | Complies |
Solubility | Soluble in ethanol, chloroform, almost insoluble in water. | Complies |
Water
|
≤0.5% | 0.1% |
ash content
|
≤0.5% | 0.2% |
Assay
|
99% | 99.80% |
Conclusion
|
Conform with the standard |